Prophylactic effects of Orthosiphon stamineus Benth. extracts on experimental induction of calcium oxalate nephrolithiasis in rats

Polysaccharides were the main therapeutic materials in Orthosiphon stamineus, playing a role as a regulator of OPN protein expression to promote urine C2O42− and Ca2+ excretion and an inhibitor of CaOx crystallization, may warrant further evaluation as a prophylactic agent for the treatment of nephrolithiasis.171