Acanthopanax senticosus has a heme oxygenase-1 signaling-dependent effect on Porphyromonas gingivalis lipopolysaccharide-stimulated macrophages

ASE has anti-inflammatory properties on P. gingivalis LPS-stimulated RAW264.7 cells through a reduction of AP-1 and NF-κB translocation, a regulation of STAP1,3 phosphorylation and a induction of HO-1 expression and activity via activation of MAPK and Nrf-2 signaling pathway.294