Tetrahydroamentoflavone (THA) from Semecarpus anacardium as a potent inhibitor of xanthine oxidase

Activity guided fractionation of Semecarpus anacardium seed yielded a potent xanthine oxidase inhibitory biflavonoid, tetrahydroamentoflavone. The compound showed a non-competitive inhibitory activity close to the standard xanthine oxidase inhibitory durg allopurinol.