کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5850647 | 1561779 | 2014 | 9 صفحه PDF | دانلود رایگان |

- Acceptability, safety and efficacy of sacha inchi oil consumption were assessed.
- Sacha inchi oil has good acceptability after one-week consumption.
- Minor side-effects were observed after 4Â months of sacha inchi oil consumption.
- Hepatic and kidney markers were not affected during 4Â months of sacha inchi oil consumption.
- LDL-cholesterol was reduced and HDL-cholesterol was increased with sacha inchi oil consumption.
The study was designed to assess acceptability and side-effects of consumption of sacha inchi oil, rich in α-linolenic acid and sunflower oil, rich in linoleic acid, in adult human subjects. Thirty subjects received 10 or 15 ml daily of sacha inchi or sunflower oil for 4 months. Acceptability was assessed with daily self-report and with a Likert test at the end of the study. Safety was assessed with self- recording of side-effects and with hepatic and renal markers. Primary efficacy variables were the change in lipid profile. Subjects reported low acceptability of sacha inchi oil at week-1 (37.5%). However, since week-6, acceptability was significantly increased to 81.25-93.75%. No differences were observed in acceptability with respect to sex or oil volume (P > 0.05). Most frequent adverse effects during first weeks of consuming sacha inchi oil or sunflower oil were nauseas. The side-effects were reduced with time. Biochemical markers of hepatic and kidney function were maintained unchanged. Serum total cholesterol and LDL cholesterol levels and arterial blood pressure were lowered with both oils (P < 0.05). Higher HDL-cholesterol was observed with sacha inchi oil at month-4. In conclusion, sacha inchi oil consumed has good acceptability after week-1 of consumption and it is safety.
Journal: Food and Chemical Toxicology - Volume 65, March 2014, Pages 168-176