Evernia prunastri and Pseudoevernia furfuraceae lichens and their major metabolites as antioxidant, antimicrobial and anticancer agents

► We investigated chemical composition of acetone extracts of two lichens species. ► Antioxidant, antimicrobial, and anticancer activities of extracts were tested. ► Antioxidant, antimicrobial, and anticancer activities of metabolites were tested. ► Tested lichen extracts and compounds demonstrated strong biological effects. ► Lichens may be used as natural antioxidant, antimicrobial and anticancer agents.