Naringin induces death receptor and mitochondria-mediated apoptosis in human cervical cancer (SiHa) cells

► Naringin inhibits the proliferation of human cervical cancer cells. ► We examine changes in the level of cell cycle distribution on SiHa cells. ► Administration of Naringin depolarize the mitochondrial membrane potential. ► Naringin enhances the expression of caspase-3, -8, and -9, p53, Bax, Fas and FADD. ► Naringin exhibits anticancer activity against SiHa cancer cells.