Prolonged consumption of flaxseed flour increases the 17β-estradiol hormone without causing adverse effects on the histomorphology of Wistar rats' penis

► We investigated the effects of prolonged consumption of flaxseed on male rats. ► We evaluated histomorphologic and hormonal parameters of male rats. ► Male rats showed increased concentrations of 17β-estradiol. ► The use of flaxseed flour did not cause adverse effects on the penis morphology.