In vivo biological activity of rocket extracts (Eruca vesicaria subsp. sativa (Miller) Thell) and sulforaphane

► High GL content accession at highest concentration was genotoxic, the rest of the accessions exhibited no genotoxicity. ► All the Eruca accessions for all the concentrations and SF were able to detoxify the genotoxic activity of hydrogen peroxide. ► Sulforaphane presented a high antigenotoxic activity. ► Health span was increased with most of SF concentrations and with low and intermediate Eruca extracts concentrations.