Effect of dietary treatment with dimethylarsinous acid (DMAIII) on the urinary bladder epithelium of arsenic (+3 oxidation state) methyltransferase (As3mt) knockout and C57BL/6 wild type female mice

► As3mt KO and WT mice were treated with DMAIII for 4 weeks in drinking water. ► No treatment-related death or whole body toxicity observed in any of the groups. ► Urothelium showed simple hyperplasia in treated KO and WT mice. ► BrdU labeling index of urothelium was significantly increased in treated KO mice.