Non-formalin fixative versus formalin-fixed tissue: A comparison of histology and RNA quality

► Tissues treated with PAXgene Tissue or formalin are morphologically comparable. ► RNA with high integrity can be purified from tissue treated with PAXgene Tissue. ► RNA from formalin fixed tissue is chemically modified and inhibits RT PCR. ► RNA from PAXgene Tissue fixed samples is free of chemical modifications. ► RT PCR results of PAXgene Tissue RNA and frozen tissue RNA are identical.