Therapeutic impact of low amplitude high frequency whole body vibrations on the osteogenesis imperfecta mouse bone

► Whole body vibration (WBV) therapeutic impacts on bone were investigated in young osteogenesis imperfecta mice (oim). ► WBV beneficial impact on the cortical bone morphology of both femur and tibia in the wild type and oim mice ► Bone volume fraction was improved in the proximal tibia of oim vibrated mice. ► WBV has beneficial impact on bending properties in wild type vibrated mice but only a positive trend in oim mice. ► Bone apposition is not significantly improved in the mid-tibia cortical and proximal tibia trabecular bone in the oim vibrated mice.