کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5890810 | 1153260 | 2012 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Low magnitude mechanical signals mitigate osteopenia without compromising longevity in an aged murine model of spontaneous granulosa cell ovarian cancer
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شناسی تکاملی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Low magnitude mechanical signals mitigate osteopenia without compromising longevity in an aged murine model of spontaneous granulosa cell ovarian cancer Low magnitude mechanical signals mitigate osteopenia without compromising longevity in an aged murine model of spontaneous granulosa cell ovarian cancer](/preview/png/5890810.png)
چکیده انگلیسی
⺠Low intensity vibration (LIV) effects on bone were examined in mice prone to granulosa cell tumorigenesis. ⺠Exposure to LIV did not compromise longevity following 1 year of daily treatment. ⺠Bone preservation was evident in tibiae and vertebrae of LIV mice as compared to controls. ⺠MSCs were significantly lower in the bone marrow of LIV-treated animals and in those lacking pathology. ⺠Overall tumor incidence was lower in LIV mice, and involved fewer organs when disease was evident.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bone - Volume 51, Issue 3, September 2012, Pages 570-577
Journal: Bone - Volume 51, Issue 3, September 2012, Pages 570-577
نویسندگان
Gabriel M. Pagnotti, Benjamin J. Adler, Danielle E. Green, M. Ete Chan, Danielle M. Frechette, Kenneth R. Shroyer, Wesley G. Beamer, Janet Rubin, Clinton T. Rubin,