Id2 controls chondrogenesis acting downstream of BMP signaling during maxillary morphogenesis

► A mouse model for postnatal jaw deformities. ► The involvement of the Id2 gene in chondrocyte differentiation, chondrocyte proliferation, and endochondral ossification in vivo. ► Id2 controls chondrogenesis by enhancing BMP signaling through inhibiting Smad7 expression.