Development of quantitative computed-tomography-based strength indicators for the identification of low bone-strength individuals in a clinical environment

► Computed-tomography-based images can provide bone-strength parameters that correlate well with finite-element-based bone-strength estimates. ► Modulus-weighted bone-strength indicators correlate better with finite-element-based bone-strength estimates than area- or density-weighted indicators. ► The weakest locations on various long bones are consistent within 0.5% of bone length.