کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5892297 1153317 2008 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Osteocyte morphology in fibula and calvaria - Is there a role for mechanosensing?
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شناسی تکاملی
پیش نمایش صفحه اول مقاله
Osteocyte morphology in fibula and calvaria - Is there a role for mechanosensing?
چکیده انگلیسی
The anisotropy of osteocytes and their alignment to the local mechanical loading condition suggest that these cells are able to directly sense matrix strains due to external loading of bone. This reinforces the widely accepted role of osteocytes as mechanosensors, and suggests an additional mode of mechanosensing besides interstitial fluid flow. The relatively spherical morphology of calvarial osteocytes suggests that these cells are more mechanosensitive than fibular osteocytes, which provides a possible explanation of efficient physiological load bearing for the maintenance of calvarial bone despite its condition of relative mechanical disuse.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bone - Volume 43, Issue 3, September 2008, Pages 452-458
نویسندگان
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