کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5896578 | 1154987 | 2010 | 14 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Surgical options in disorders of sex development (dsd) with ambiguous genitalia
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کلمات کلیدی
Social identity - هویت اجتماعی Urethroplasty - اورترپلاستیکAmbiguous genitalia - تناسلی متضادMixed gonadal dysgenesis - دیسژنز گناد مختلطFeminisation - زنانگیSexual identity - هویت جنسیIndividual identity - هویت فردیCongenital adrenal hyperplasia - هیپرپلازی آدرنال مادرزادیHypospadias - هیپوسپادیاسVaginoplasty - واژینوپلاستیurethral plate - ورید مجرای ادرارperineoplasty - پرینوپلاستیMasculinisation - گرایش جنسی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
علوم غدد
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Disorders of sexual development (DSD) include three main groups of patients: (1) The virilised 46,XX DSD essentially represented by congenital adrenal hyperplasia (CAH) ; (2) The undervirilised 46,XY DSD essentially represented by hypospadias; and (3) the chromosomic jigsaws essentially represented by mixed gonadal dysgenesis. It is in this last group that gender assignment remains a difficult decision involving various indicators, which can be split into four categories: (1) the inside sex (i.e., genes, hormones and target tissues); (2) the outside sex (i.e., anatomy of genitalia including size of the genital tubercle, mullerian cavity and potential adult height of the patient); (3) the functional sex (i.e., potential sexuality and fertility); and (4) and the social sex (i.e., the cultural medium in which the child is brought up). The challenge is to outline the future individual identity of the child in the postnatal period using these indicators. Current evolutions of surgical techniques of 'feminisation' and 'masculinisation' are described as well as their outcomes.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Best Practice & Research Clinical Endocrinology & Metabolism - Volume 24, Issue 2, April 2010, Pages 311-324
Journal: Best Practice & Research Clinical Endocrinology & Metabolism - Volume 24, Issue 2, April 2010, Pages 311-324
نویسندگان
Isabelle (Chief Resident in Paediatric Surgery), Daniela Brindusa (Consultant in Paediatric Surgery), Elodie (Resident in Paediatric Surgery), Claire-Lise (Consultant in Paediatric Endocrinology), Pierre (Professor of Paediatric Endocrinology),