The lack of association between interleukin-6 gene − 174 G/C polymorphism and the risk of type 1 diabetes mellitus: A meta-analysis of 18,152 subjects

► We performed a meta-analysis to derive a more precise estimation of the relationship. ► Our study has the potential to detect small effects in genetic association studies. ► Our study suggests that IL-6 gene polymorphism is not associated with T1DM risk.