Review“Omics” in the study of the major parasitic diseases malaria and schistosomiasis

- A review of identification of new drugs and vaccine candidates based on “omics” data.
- Genomics, transcriptomics and proteomics have provided a huge amount of information.
- Mining useful information is challenging.
- Bioinformatic tools have been used to search for new drugs and vaccine candidates.
- Schistosoma and Plasmodium data were reviewed to provide a list of new drugs and vaccine candidates.

Genomic, transcriptomic, proteomic, and metabolomic projects exemplify the “omics” era, and have significantly expanded available data for biomedical research. Recently, next generation sequencing technologies have even more greatly expanded DNA and RNA information. The present challenge is mining this information to obtain meaningful data such as that identifying novel drug targets and vaccine candidates. Several bioinformatics tools and new technologies have been used to high-throughput identification of potential candidates. We illustrate the utilization of new strategies in the study of two major parasitic diseases: schistosomiasis and malaria.