CCL3L1 copy number and susceptibility to malaria

► We model, for the first time, CCL3L1 copy number variation and susceptibility to malaria. ► Association analysis was performed using family-based methods in a Tanzanian population. ► We question whether malaria has shaped the current spectrum of variation observed at CCL3L1. ► We identify a weak association between CCL3L1 copy number and haemoglobin concentration.