کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5945315 | 1172350 | 2014 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Arterial stiffness in patients with non-alcoholic fatty liver disease is related to fibrosis stage and epicardial adipose tissue thickness
ترجمه فارسی عنوان
سختی شریان در بیماران مبتلا به بیماری کبدی چربی غیر الکلی مربوط به مرحله فیبروز و ضخامت بافت اپیکاردی بافت چربی است
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کلمات کلیدی
بیماری کبدی چربی غیر الکلی، سختی شریان، سرعت موج پالس، شاخص افزایش، ضخامت چربی اپیکاردی،
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
چکیده انگلیسی
Objective: Non-alcoholic fatty liver disease (NAFLD) is associated with atherosclerosis and reduced vascular compliance. The purpose of this study was to examine the relationships between arterial stiffness measures, the histological severity of NAFLD, and epicardial fat thickness (EFT). Methods: A total of 100 patients with biopsy-proven NAFLD and 50 age- and sex-matched controls were enrolled. The histological severity was assessed in all NAFLD patients. Measurements of arterial stiffness [pulse-wave velocity (PWV) and augmentation index (AIx)] were carried out using a Mobil-O-Graph arteriograph system. EFT was assessed by means of echocardiography. Results: Compared with controls, NAFLD patients had significantly higher PWV and AIx values. Stepwise linear regression analysis demonstrated that the liver fibrosis score and EFT were independent predictors of both PWV and AIx values in NAFLD patients. Conclusions: Patients with NAFLD have an increased arterial stiffness, which reflects both the severity of liver fibrosis and increased EFT values.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Atherosclerosis - Volume 237, Issue 2, December 2014, Pages 490-493
Journal: Atherosclerosis - Volume 237, Issue 2, December 2014, Pages 490-493
نویسندگان
Murat Sunbul, Mehmet Agirbasli, Erdal Durmus, Tarik Kivrak, Hakan Akin, Yucel Aydin, Rabia Ergelen, Yusuf Yilmaz,