Endogenous CETP activity as a predictor of cardiovascular risk: Determination of the optimal range

► LDL-C, HDL-C and TG represent strong and independent predictors of plasma CETP activity. ► CETP activity integrates major plasma lipid levels known as independent risk factors. ► A plasma CETP activity above 34% is associated with an elevated cardiovascular risk. ► A CETP activity between 22% and 34% represents the future clinical therapeutic goal.