کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5954786 | 1173322 | 2014 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Small Airway-Centered Granulomatosis Caused by Long-term Exposure to Polytetrafluoroethylene
ترجمه فارسی عنوان
گرانولوماتوز کوچک متمرکز شده در مسیر هوایی ناشی از مواجه شدن طولانی مدت با پلی تترافورو اتیلن
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کلمات کلیدی
PTFEEDSAluminum - آلومینیوم Energy-Dispersive X-ray Spectroscopy - اشعه ماوراء بنفش اشعه ایکس انرژیsilicon - سیلیسیم FT-IR - طیف سنجی مادون قرمز تبدیل فوریهFourier transform infrared spectroscopy - طیف سنجی مادون قرمز تبدیل فوریه یا طیف سنجی FTIRElectron microscopy - میکروسکوپ الکترونیpolytetrafluoroethylene - پلی تترافلورو اتیلن
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
چکیده انگلیسی
To date, there have been no reports of chronic pulmonary granulomatosis associated with exposure to polytetrafluoroethylene (PTFE). Here, we report three cases of small airway-centered granulomatous lesions in workers employed at facilities that apply coatings to pans and other utensils. The workers were repeatedly exposed to PTFE particles that were probably generated by the drying process when PTFE coatings are dried in a convection oven at high temperatures (380-420°C). The duration of inhalational PTFE exposure was between 7 and 20 years. We found granulomatous lung lesions around the small airways in lung biopsy specimens obtained from the workers. Scanning electron microscopy/energy-dispersive x-ray spectroscopy analysis was performed focusing on areas where the PTFE particles were suspected to be located in macrophages. The scanning electron microscopy/energy-dispersive x-ray spectroscopy analyses revealed fluorine in the particles. Lung tissue samples from all cases were analyzed using a fully automated Fourier transform infrared spectrometer. Analysis of the spectrum extracted from the position of the foreign particles enabled precise identification of the foreign bodies as PTFE. Fourier transform infrared revealed that all of the lung tissue samples had bands at 1, 202 to 1, 148 cmâ1 and 1, 202 to 1, 146 cmâ1, which are characteristic of the asymmetric and symmetric stretching vibrations of the C-F bonds of PTFE. These cases suggest that recurrent inhalational exposure to PTFE particles causes chronic pulmonary granulomatosis.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chest - Volume 145, Issue 6, June 2014, Pages 1397-1402
Journal: Chest - Volume 145, Issue 6, June 2014, Pages 1397-1402
نویسندگان
Won-Il MD, PhD, Hye Ra MD, Esmeralda MD, Byung Hak MD, Mi-Young MD, PhD, Kun Young MD, PhD,