Clinical Characteristics, Management, and Outcomes of Hospitalized Heart Failure in a Chinese Population-The Hong Kong Heart Failure Registry

- The rates of new heart failure (HF) hospitalization among Chinese in Hong Kong between 2005 and 2012 were 0.59 per 1000 population per year for males and 0.58 per 1000 population per year for females.
- In contrast to epidemiological studies from other Asian countries, the most prevalent comorbidities in our cohort were hypertension (69.8%) and coronary heart disease (29.3%).
- The prognosis of new-onset HF was poor with high all-cause mortality and cardiovascular mortality for both HF with preserved ejection fraction and HF with reduced ejection fraction.

BackgroundEpidemiological data for heart failure (HF) in the Chinese population is scarce. In this study, we described the clinical characteristics and outcomes of new-onset HF in our population.Methods and ResultsWe conducted a retrospective, observational study on consecutive Chinese patients hospitalized for new-onset HF between 2005 and 2012 in our center. A total of 1940 patients (mean age, 78.2 ± 11.8 years, 54.2% female) were identified. The rate of new HF hospitalization was 0.59 per 1000 population. The most prevalent comorbidities were hypertension (69.8%) and coronary artery disease (29.3%), and 52.3% had HF with preserved ejection fraction (HFpEF). The all-cause mortality was 19.5% at 1 year, 32.1% at 2 years, and 54% at 5 years. Cardiovascular mortality was 7.2% at 1 year, 11.8% at 2 years, and 20.7% at 5 years. No difference in all-cause mortality or cardiovascular mortality was observed between those with HF with reduced ejection fraction than HFpEF.ConclusionsOur patients with new-onset HF shared similar clinical characteristics with the Caucasian population. The prognosis was poor with high all-cause mortality for both HFpEF and HF with reduced ejection fraction.