Drug-loading of poly(ethylene glycol methyl ether methacrylate) (PEGMEMA)—based micelles and mechanisms of uptake in colon carcinoma cells

• PEGMEMA-based micelles can rapidly deliver low doses of chemotherapeutics to cancer cells.
• PEGMEMA-based micelles provide controlled release of drugs over 16 days in vitro.
• Drug loaded increases cellular uptake.
• Polymeric micelle uptake predominantly via passive mechanisms.