کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
599267 1454269 2015 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effect of layer-by-layer coatings and localization of antioxidant on oxidative stability of a model encapsulated bioactive compound in oil-in-water emulsions
ترجمه فارسی عنوان
اثر پوشش های لایه و موضع گیری آنتی اکسیدان بر پایداری اکسیداتیو یک ترکیب شیمیایی بسته بندی شده با قابلیت فعال در امولسیون های نفت در آب
کلمات کلیدی
محلی سازی آنتی اکسیدان، لایه های لایه پوشش، اکسیداسیون ناشی از رادیکال آزاد، ترکیبات بیولوژیکی، امولسیون با پوشش های ساختار یافته بین فاز
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی شیمی کلوئیدی و سطحی
چکیده انگلیسی


• Polymer with conjugated antioxidant has improved radical scavenging property.
• Localization of antioxidants at the emulsion interface improves oxidative stability.
• Layer-by-layer polymer coatings had limited impact on oxidative barrier properties.

Oxidation of encapsulated bioactives in emulsions is one of the key challenges that limit shelf-life of many emulsion containing products. This study seeks to quantify the role of layer-by-layer coatings and localization of antioxidant molecules at the emulsion interface in influencing oxidation of the encapsulated bioactives. Oxidative barrier properties of the emulsions were simulated by measuring the rate of reaction of peroxyl radicals generated in the aqueous phase with the encapsulated radical sensitive dye in the lipid core of the emulsions. The results of peroxyl radical permeation were compared to the stability of encapsulated retinol (model bioactive) in emulsions. To evaluate the role of layer-by-layer coatings in influencing oxidative barrier properties, radical permeation rates and retinol stability were evaluated in emulsion formulations of SDS emulsion and SDS emulsion with one or two layers of polymers (ϵ-polylysine and dextran sulfate) coated at the interface. To localize antioxidant molecules to the interface, gallic acid (GA) was chemically conjugated with ϵ-polylysine and subsequently deposited on SDS emulsion based on electrostatic interactions. Emulsion formulations with localized GA molecules at the interface were compared with SDS emulsion with GA molecules in the bulk aqueous phase. The results of this study demonstrate the advantage of localization of antioxidant at the interface and the limited impact of short chain polymer coatings at the interface of emulsions in reducing permeation of radicals and oxidation of a model encapsulated bioactive in oil-in-water emulsions.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Colloids and Surfaces B: Biointerfaces - Volume 135, 1 November 2015, Pages 472–480
نویسندگان
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