Functionalized graphene oxide as a drug carrier for loading pirfenidone in treatment of subarachnoid hemorrhage

- Synthesize FGO nanosheet loading drug pirfenidone to treat subarachnoid hemorrhage.
- Pirfenidone-FGO can monitor brain tissue and treat SAH disease simultaneously.
- Introduce Tat peptide and mPEG chain onto GO nanosheet to enhance treatment efficacy.
- Pirfenidone-FGO exhibits a better treatment efficacy than the single pirfenidone.
- FGO is used to real-time monitoring with deep resolution of brain tissues after SAH.