The nano-plasma interface: Implications of the protein corona

- The nano-plasma interface consists of interactions between nanoparticles and plasma proteins.
- The properties of nanoparticles and biomolecules change at the nano-plasma interface.
- This impacts nanoparticle toxicity, biodistribution, cell interactions, and drug release.
- The properties of the interface dictate the biocompatibility and efficacy of nanotherapeutics.
- The nano-plasma interface poses challenges and opportunities for nanomedicine.