Safe and efficient pH sensitive tumor targeting modified liposomes with minimal cytotoxicity

- We prepared a kind of safe and efficient tumor targeting drug carrier OPLPs.
- “Anchor-chain” molecule PASP-g-C8 was designed and synthesized to make OPLPs stable and pH sensitive.
- OPLPs are consisted of liposomes and biocompatible molecule PASP-g-C8 and obtained just based on physical reaction.
- 70 percent of tumor cells were killed while all normal cells keep viable in 48 h when treated with OPLPs.