Bactericidal evaluation of N-halamine-functionalized silica nanoparticles based on barbituric acid

- Novel N-halamine-functionalized silica nanoparticles were facilely fabricated from 5-allylbarbituric acid by a seeded copolymerization.
- Barbituric acid-based N-halamine nanoparticles have higher bactericidal activity than hydantoin-based N-halamine nanoparticles.
- Effects of silica support and comonomer methyl methacrylate on particles morphology and antimicrobial activity were systematically investigated.