کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
600137 1454297 2013 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Synthesis and cellular compatibility of biomineralized Fe3O4 nanoparticles in tumor cells targeting peptides
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی شیمی کلوئیدی و سطحی
پیش نمایش صفحه اول مقاله
Synthesis and cellular compatibility of biomineralized Fe3O4 nanoparticles in tumor cells targeting peptides
چکیده انگلیسی

Fe3O4 nanoparticles (NPs) coated with WSG-peptide were prepared via a facile biomineralization technique at room temperature. The concentration of the peptides and the mixing time could substantially influence the morphology of as-prepared particles. The saturation magnetization of WSG-coated Fe3O4 particles were 35.92 emu/g, slightly higher than that of Fe3O4 without WSG peptides. Cell viability assay revealed that WSG-coated Fe3O4 particles had a good cellular compatibility. In addition, compared with Fe3O4 NPs, the mineralized Fe3O4 NPs coated with WSG peptides could more easily assemble into the cancer cell, indicating that the WSG-Fe3O4 NPs possess cancer targeting property. Thus, the WSG-coated Fe3O4 NPs could be used in cancer diagnosis and treatment fields.

The morphology of biomineralized nanoparticles is influenced by the organic templates.Figure optionsDownload as PowerPoint slideHighlights
► Fe3O4 NPs coated with WSG-peptide were prepared via a biomineralization technique.
► WSG-coated Fe3O4 particles had a good cellular compatibility.
► WSG-Fe3O4 NPs possess a cancer targeting property.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Colloids and Surfaces B: Biointerfaces - Volume 107, 1 July 2013, Pages 180–188
نویسندگان
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