کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6004874 | 1579572 | 2008 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Spinal cord transection modifies ileal fluid and electrolyte transport in rats
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب سلولی و مولکولی
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چکیده انگلیسی
Spinal cord injury (SCI) is associated with severe autonomic changes, including inhibition of gastrointestinal (GI) motility. GI motility changes are known to affect electrolytes transport and these changes have not been adequately studied after SCI. We studied the ileal permeability to fluid and electrolytes in rats submitted to experimental spinal cord transection (SCT), between T4 and T5, throughout the first week after SCT. SCT increased ileal secretion of Na+ (PÂ <Â 0.05) and decreased the Clâ absorption during the first week post SCI (PÂ <Â 0.05). Water transport was also significantly altered, leading to increased water secretion following the Na+ gradient. Ileal secretion of K+ was significantly increased 1 and 7Â days after spinal cord injury. To our knowledge, the present findings are the first direct evidence that SCT alters ileal electrolyte transport in rats. Further studies are necessary to evaluate the mechanisms involved in this phenomenon.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Autonomic Neuroscience - Volume 139, Issues 1â2, 30 May 2008, Pages 24-29
Journal: Autonomic Neuroscience - Volume 139, Issues 1â2, 30 May 2008, Pages 24-29
نویسندگان
Bruno Amaral Medeiros, Camila Linhares dos Santos, Raimundo Campos Jr., Dário Augusto Ferreira de Queiroz, José Ronaldo Vasconcelos da Graça, Armenio Aguiar dos Santos, Francisco Hélio Rola, Aldo Ãngelo Moreira Lima,