Nanospines incorporation into the structure of the hydrophobic cryogels via novel cryogelation method: An alternative sorbent for plasmid DNA purification

► Nanospines incorporation into the cryogel structure. ► Hydrophobic cryogels as an alternative sorbent for plasmid DNA purification. ► Surface area enhancement by modified cryogelation approach. ► Evaluation of chromatographic performance of the cryogel by means of FPLC. ► Plasmid DNA isolation from Escherichia coli lysate.