Effect of Al2O3 nanoparticles on bacterial membrane amphiphilic biomolecules

► Al2O3 NPs disperse lipopolysaccharide vesicles. ► Lipopolysaccharides coat on Al2O3 NPs due to strong adsorption. ► Diameters of phospholipid vesicles increase after exposing to Al2O3 NPs. ► The aqueous stability of phospholipid is disturbed by Al2O3 NPs.