Facile green synthesis of gold nanoparticles using leaf extract of antidiabetic potent Cassia auriculata

► In the present work synthesis of gold nanoparticles has been carried out using Cassia auriculata an antidiabetic potent plant. The main aim of the present investigation is to emphasize that the role of stabilizing and capping molecules may promote the activity of gold nanoparticles in drug delivery applications. The biocompatibility and the less toxic nature of the gold nanoparticles coupled with stabilizing compounds of antidiabetic plant may induce a hypoglycemic effect. ► Characterization techniques such as UV-vis to check the surface plasmon resonance in the reduction of auric chloride, FT-IR to find out the possible biomolecules involved in the stabilization and capping of gold nanoparticles, TEM to elucidate the size and shape, SEM to check the surface morphology, EDAX to find out the elemental composition and XRD for crystalline nature were carried out. ► The average size 15-25 nm and other standard characterizations were also done. The gold nanoparticles were stable at a wide range of pH [3.4-10.2] which can be used for drug delivery applications. Selection of medicinal value plants in synthesis of gold nanoparticles will create a new platform to utilize the potential of herbal medicine in nanoscience for drug delivery and biomedical applications.