Preparation and characterization of zein/chitosan complex for encapsulation of α-tocopherol, and its in vitro controlled release study

► Zein/CS nanocomplex could be considered as a polyelectrolyte complex based on our results. ► The hydrogen bonds and hydrophobic interactions could induce the formation of nanoparticles. ► The nanocomplex had spherical shape and uniform diameter about 200-300 nm. ► The complex could provide controlled release of α-tocopherol and protection from degrading in GI tract.