کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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601649 | 879949 | 2009 | 6 صفحه PDF | دانلود رایگان |
Biphasic calcium phosphate nanoparticles comprising both hydroxyapatite (HA) and β polymorph of tricalcium phosphate (β-TCP) have been synthesized together by a polymer matrix mediated process. The process, based on in situ mineralization of poly (vinyl alcohol), exerts a good control over the morphological features of biphasic nanoparticles. By controlling the reaction chemistry (Ca:P ratios), nanobioceramic particles having three different HA/β-TCP ratios of 50:50, 55:45 and 60:40 respectively. As the two constituents of biphasic system (HA and β-TCP) facilitate series of signaling cascades in osteoblast division and differentiation, the adhesion and differentiation properties of mesenchymal cells (MSCs) derived from bone marrow has been studied.
Journal: Colloids and Surfaces B: Biointerfaces - Volume 73, Issue 1, 1 October 2009, Pages 146–151