Solubilization of resveratrol in micellar solutions of different bile acids

Solubilizated resveratrol was quantified using HPLC system with UV detection. Membranolytical potential was determined from citrate rabbit blood. Structures of mixed micelles of each bile acid and resveratrol were explained, and multiple linear regression equations for solubilization of resveratrol on different concentrations of bile acids were obtained. Micellar solution of 3,7,12-TCA had the biggest affinity for resveratrol solubilization and then, in decreasing order 7-MCA > 7, 12-DCA > 12-MCA > 12-MDCA > CA. Also, 3,7,12-TCA had the lowest membranolytical potential.