ReviewNeuroimaging in aphasia treatment research: Issues of experimental design for relating cognitive to neural changes

The design of functional neuroimaging studies investigating the neural changes that support treatment-based recovery of targeted language functions in acquired aphasia faces a number of challenges. In this paper, we discuss these challenges and focus on experimental tasks and experimental designs that can be used to address the challenges, facilitate the interpretation of results and promote integration of findings across studies.

► Experimental design issues in functional neuroimaging research on aphasia treatment ► Using fMRI to identify neural changes supporting treatment and recovery in aphasia ► Relating treatment-based changes in language functions to associated neural changes