Bridging the hemispheres in meditation: Thicker callosal regions and enhanced fractional anisotropy (FA) in long-term practitioners

► The corpus callosum was analyzed in 30 meditators and 30 well-matched controls. ► DTI-based measures were used in combination with MRI-based measures. ► Callosal measures were larger in meditators, particularly in anterior sections. ► Effects were stronger locally (point-wise) than globally (segment-specific). ► Effects were more prominent for microscopic than macroscopic characteristics.