Association between hippocampal volume and P300 event related potential in psychosis: Support for the Kraepelinian divide

►Hippocampal volume and P300 ERP abnormalities are found in psychotic disorders. ►Hippocampus is postulated to be one of the main P300 generators. ►However, the relationship between these two consistent biomarkers is not well known. ►Novel SUR method used in family study to explore brain volume and ERP relationship. ►Association between these markers demonstrates support for Kraepelinian dichotomy.