Altered spontaneous activity in Alzheimer's disease and mild cognitive impairment revealed by Regional Homogeneity

►ReHo was used to explore activities among NC, MCI and AD for the first time. ►Altered ReHo were found in default mode network in both MCI and AD. ►Significant correlation between the ReHo and clinical variables were found in AD/MCI. ►ReHo is a feature to classify patients from NC.