Coordinate-based meta-analysis of experimentally induced and chronic persistent neuropathic pain

► Metastudy over 53 fMRI-studies investigating the cerebral representation of pain ► Differences between experimentally induced (n = 36) and neuropathic pain (n = 17) ► Experimentally induced pain was compared between thermal (n = 18) and non-thermal ► Neuropathic pain showed increased left S2, ACC, and right anterior insula activation ► S1 was only involved during non-thermal experimentally induced pain