Projecting out muscle artifacts from TMS-evoked EEG

► TMS of areas near cranial muscles produces large muscle artifacts. ► The muscle artifacts mask early (< 50 ms) TMS-evoked brain signals. ► At high (> 100 Hz) frequencies, only muscle signal is present. ► Projecting out > 100 Hz muscle components also reduces < 100 Hz muscle components. ► The signal-to-artifact ratio is increased as a result of the projections.