کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6041568 | 1189301 | 2014 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A systematic review and meta-analysis on the epidemiology of Duchenne and Becker muscular dystrophy
ترجمه فارسی عنوان
یک بررسی سیستماتیک و متاآنالیز در اپیدمیولوژی دیستروفی عضلانی دوشن و بکر
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کلمات کلیدی
BMDDMDEpidemiology - اپیدمیولوژی(همهگیرشناسی)Incidence - بروز Becker muscular dystrophy - دیستروفی عضلانی بکرDuchenne muscular dystrophy - دیستروفی عضلانی دوشنMuscular dystrophy - دیستروفی ماهیچهای، دیستروفی عضلانیPrevalence - شیوعconfidence interval - فاصله اطمینانPopulation-based - مبتنی بر جمعیت
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب تکاملی
چکیده انگلیسی
The muscular dystrophies are a broad group of hereditary muscle diseases with variable severity. Population-based prevalence estimates have been reported but pooled estimates are not available. We performed a systematic review of worldwide population-based studies reporting muscular dystrophies prevalence and/or incidence using MEDLINE and EMBASE databases. The search strategy included key terms related to muscular dystrophies, incidence, prevalence and epidemiology. Two reviewers independently reviewed all abstracts, full text articles and abstracted data using standardized forms. Pooling of prevalence estimates was performed using random effect models. 1104 abstracts and 167 full text articles were reviewed. Thirty-one studies met all eligibility criteria and were included in the final analysis. The studies differed widely in their approaches to case ascertainment, resulting in significant methodological heterogeneity and varied data quality. The pooled prevalence of DMD and BMD was 4.78 (95% CI 1.94-11.81) and 1.53 (95% CI 0.26-8.94) per 100,000 males respectively. The incidence of DMD ranged from 10.71 to 27.78 per 100,000. This is the first meta-analysis of worldwide prevalence estimates for muscular dystrophies. There is a need for more epidemiological studies addressing global estimates on incidence and prevalence of muscular dystrophies, utilizing standardized diagnostic criteria as well as multiple sources of case ascertainment.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuromuscular Disorders - Volume 24, Issue 6, June 2014, Pages 482-491
Journal: Neuromuscular Disorders - Volume 24, Issue 6, June 2014, Pages 482-491
نویسندگان
Jean K. Mah, Lawrence Korngut, Jonathan Dykeman, Lundy Day, Tamara Pringsheim, Nathalie Jette,