A randomized controlled trial to evaluate the effectiveness of CouPLES: A spouse-assisted lifestyle change intervention to improve low-density lipoprotein cholesterol

► Low-density lipoprotein cholesterol decreased in intervention and usual care groups. ► Dietary intake improved in the intervention group relative to the usual care group. ► Moderate intensity physical activity improved marginally in the intervention group. ► Most participants did not change cholesterol medication usage during the study.