Histomorphometric and Micro-computed Tomography Analysis of Pulpal Response to Three Different Pulp Capping Materials

Reparative hard tissue formation in pulps capped with Portland cement-based materials differs only in quantity (thickness) but not in quality from those that were formed after direct pulp capping with calcium hydroxide. It appears that other growth factors and up-regulation of transcription factors are required apart from those sequestered via the application of alkaline pulp capping materials for dental pulp stem cells to commit to the odontoblast lineage.