کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6081810 | 1205676 | 2013 | 8 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Psychiatric-Medical Comorbidity1Preexisting depressive symptoms are associated with long-term cognitive decline in patients after cardiac surgery Psychiatric-Medical Comorbidity1Preexisting depressive symptoms are associated with long-term cognitive decline in patients after cardiac surgery](/preview/png/6081810.png)
ObjectiveTo examine whether preoperative psychological dysfunctions rather than intraoperative factors may differentially predict short- and long-term postoperative cognitive decline (POCD) in patients after cardiac surgery.MethodForty-two patients completed a psychological evaluation, including the Trail Making Test Part A and B (TMT-A/B), the memory with 10/30-s interference, the phonemic verbal fluency and the Center for Epidemiological Studies of Depression (CES-D) scale for cognitive functions and depressive symptoms, respectively, before surgery, at discharge and at 18-month follow-up.ResultsTen (24%) and 11 (26%) patients showed POCD at discharge and at 18-month follow-up, respectively. The duration of cardiopulmonary bypass significantly predicted short-term POCD [odds ratio (OR)=1.04, P<Â .05], whereas preoperative psychological factors were unrelated to cognitive decline at discharge. Conversely, long-term cognitive decline after cardiac surgery was significantly predicted by preoperative scores in the CES-D (OR=1.26, P<Â .03) but not by intraoperative variables (all Ps >Â .23).ConclusionsOur findings showed that preexisting depressive symptoms rather than perioperative risk factors are associated with cognitive decline 18 months after cardiac surgery. This study suggests that a preoperative psychological evaluation of depressive symptoms is essential to anticipate which patients are likely to show long-term cognitive decline after cardiac surgery.
Journal: General Hospital Psychiatry - Volume 35, Issue 5, SeptemberâOctober 2013, Pages 472-479