کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6082543 1205696 2013 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Psychiatry and Primary CarePersistence of antidepressant treatment for depressive disorder in Taiwan
ترجمه فارسی عنوان
روانپزشکی و مراقبت های اولیه تداوم درمان ضد افسردگی برای اختلال افسردگی در تایوان
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی طب اورژانس
چکیده انگلیسی

ObjectWe sought to explore factors associated with persistence of antidepressant treatment in Taiwan and to compare persistence rates across various antidepressants.MethodThis was a retrospective cohort study using medical claims in Taiwan. We collected data of all new antidepressant users with depressive disorder, aged 18 years or older, during the study period from January 1, 1998, to July 4, 2009. Overall antidepressant treatment persistence was defined as undergoing treatment for 180 days without exceeding a 30-day gap. We also assess the cause of treatment change of initial monotherapy, including discontinuation, switching or combination. The competing risks method was used to estimate cause-specific cumulative incidence and to determine associated factors.ResultsOnly 17.4% of patients continued overall antidepressant treatment and 7.6% continued initial antidepressant monotherapy for 180 days or more. Most patients change initial monotherapy through discontinuation, followed by switching and combination. Male gender, older age, comorbidity with anxiety or sleep disorders, and more concomitant use of drugs were associated with lower discontinuation rate. In terms of antidepressant comparisons, we found that patients treated with selective serotonin reuptake inhibitors are less likely to change initial monotherapy.ConclusionThe overall persistence of antidepressant treatment in Taiwan was lower than in other countries.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: General Hospital Psychiatry - Volume 35, Issue 3, May–June 2013, Pages 279-285
نویسندگان
, , , , , , ,