|کد مقاله||کد نشریه||سال انتشار||مقاله انگلیسی||ترجمه فارسی||نسخه تمام متن|
|6089173||1208537||2016||6 صفحه PDF||سفارش دهید||دانلود رایگان|
- Plasma fat soluble nutrients were assessed in children before and after intervention with fish oil or oily fish.
- Most of the children were deficient in vitamin D at baseline before supplementation.
- Fish oil and fish meal improved plasma beta carotene, but not vitamin A or E levels.
- Vitamin D deficiency was improved by supplementation with fish oil devoid of the vitamin.
ObjectivesOver the past two decades, the Omani diet has changed considerably to resemble a high calorie and a low nutrient density Western diet. We investigated the fat soluble nutrient status of children before and after intervention with fish diet or fish oil.MethodsChildren ages 9 and 10 y (n = 314) were recruited from three randomly selected schools. The schools were assigned to a fish, fish oil, or control group and the children were given a lightly grilled oily fish, a re-esterified triacylglycerol fish oil capsule, or no fish for 12 wk.ResultsPlasma vitamin A, beta carotene, vitamin E concentrations, and vitamin E/total lipid ratio at baseline were 2.7Â Â±Â 0.85Â Î¼mol/L, 0.68Â Â±Â 0.48Â Î¼mol/L, 21.1Â Â±Â 4.8Â Î¼mol/L, and 5.0Â Â±Â 0.81Â Î¼mol/mmol, respectively, and none of the children were deficient. They were severely deficient (<27.5Â nmol/L; 10.5% boys and 28.5% girls), deficient (27.5-44.9Â nmol/L; 47.6% boys and 49.4% girls) or insufficient (50-74.9Â nmol/L; 34.6% boys and 21.5% girls) in vitamin D; only 7.3% boys and 0.6% girls had optimal status (â¥75Â nmol/L). Parathyroid hormone (5.0Â Â±Â 1.7 versus 5.8Â Â±Â 2.1 pmol/L; PÂ <Â 0.0001) and alkaline phosphatase (225.2Â Â±Â 66.6 versus 247.8Â Â±Â 73.7 U/L; PÂ <Â 0.01) levels were lower in boys. Postintervention, the fish oil (54.1Â Â±Â 17.5Â nmol/L; PÂ <Â 0.001) and fish (49.2Â Â±Â 17.4Â nmol/L; PÂ <Â 0.05) groups had elevated levels of vitamin D compared with the controls (42.3Â Â±Â 17.5Â nmol/L).ConclusionsVitamin D deficiency is prevalent in Omani school children, but it can be mitigated with omega-3 fatty acid supplementation. Vitamin D plays a crucial role in skeletal and extraskeletal systems. Hence, there is a need for a child-focused program of food fortification and outdoor activities to alleviate the problem.
Journal: Nutrition - Volume 32, Issue 1, January 2016, Pages 73-78