کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6109591 | 1211209 | 2009 | 13 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Non-invasive assessment and quantification of liver steatosis by ultrasound, computed tomography and magnetic resonance
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کلمات کلیدی
1H MRSSVSMDCTSNRNAFLDALD - آدرنولکودیستروفیHepatic steatosis - استئاتوز کبدیNon-alcoholic steatohepatitis - استئاتوهپاتیت غیرالکلیIdeal - ایده آلSteam - بخارalcoholic liver disease - بیماری کبدی الکلیnon-alcoholic fatty liver disease - بیماری کبدی چربی غیر الکلیTesla - تسلاMagnetic resonance - تشدید مغناطیسیcomputed tomography - توموگرافی کامپیوتری یا سی تی اسکن یا مقطعنگاری رایانهایIn-phase - در فازecho time - زمان اکوRepetition time - زمان تکرارSignal-to-noise - سیگنال به نویزMulti-detector row CT - سیگنال ردیف چند آشکارسازProton magnetic resonance spectroscopy - طیف سنجی رزونانس مغناطیسی پروتونUltrasound - فراصوتPRESS - مطبوعاتpoint resolved spectroscopy - نقطه طیف سنجی حل شدهNash - نوشHounsfield units - واحدهای هونسفیلد
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
بیماریهای گوارشی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Hepatic steatosis is the most prevalent liver disorder in the developed world. It is closely associated with features of metabolic syndrome, especially insulin resistance and obesity. The two most common conditions associated with fatty liver are alcoholic liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD). Liver biopsy is considered the gold standard for the assessment of liver fat, but there is a need for less invasive diagnostic techniques. New imaging modalities are emerging, which could provide more detailed information about hepatic tissue or even replace biopsy. In the present review, available imaging modalities (ultrasound, computed tomography, magnetic resonance imaging and proton magnetic resonance spectroscopy) are presented which are employed to detect or even quantify the fat content of the liver. The advantages and disadvantages of the above-mentioned imaging modalities are discussed. Although none of these techniques is able to differentiate between microvesicular and macrovesicular steatosis and to reveal all features visible using histology, the proposed diagnostic modalities offer a wide range of additional information such as anatomical and morphological information non-invasively. In particular, magnetic resonance imaging and proton magnetic resonance spectroscopy are able to quantify the hepatic fat content hence avoiding exposure to radiation. Except for proton magnetic resonance spectroscopy, all modalities offer additional information about regional fat distribution within the liver. MR elastography, which can estimate the amount of fibrosis, also appears promising in the differentiation between simple steatosis and steatohepatitis.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Hepatology - Volume 51, Issue 3, September 2009, Pages 433-445
Journal: Journal of Hepatology - Volume 51, Issue 3, September 2009, Pages 433-445
نویسندگان
Nina F. Schwenzer, Fabian Springer, Christina Schraml, Norbert Stefan, Jürgen Machann, Fritz Schick,